Chemoenzymatic preparation of germacrene analogues

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Chemoenzymatic preparation of germacrene analogues.

A small library of novel germacrenes was generated using a combination of two plant enzymes, germacrene A synthase, and D synthase and modified farnesyl diphosphate (FDP) analogues. This chemoenzymatic approach allows the preparation of potentially valuable volatiles for biological studies.

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ژورنال

عنوان ژورنال: Chemical Communications

سال: 2012

ISSN: 1359-7345,1364-548X

DOI: 10.1039/c2cc35542f